RESULTS BY TARGET PROTEIN
CD3 (coming soon)
• Caspase-3 (coming soon)
• Dystrophin (coming soon)
• Laminin (coming soon)
The FC3R aims to replace the use of antibodies of animal origin, which present both ethical and scientific robustness problems (variability, lack of reproducibility, etc.). The antibodies most commonly used on French histology platforms have been targeted as a priority. In partnership with the Association Française d'Histotechnologie (AFH) and antibody suppliers, a pilot study was carried out to characterise the performance of alternative recombinant antibodies and share the results with the scientific community.
CD3 (coming soon)
• Caspase-3 (coming soon)
• Dystrophin (coming soon)
• Laminin (coming soon)
National survey (2024)
Which animal-derived antibodies are most commonly used on histology platforms in France?
Survey drawn up with the Association Française d’Histotechnologie
12 responding national platforms
Identification of 36 antibodies ‘to be replaced’
Pilot study (2024-2025)
Characterisation and validation
of recombinant alternatives
Selection of 12 target proteins
3 recombinant antibodies for each target protein sent by partner suppliers
Characterisation/validation by histology platforms
Sharing of results (from 2025)
Dissemination of protocols and data obtained
Publications on the FC3R website
Conference presentation (AFH)
Publications (Short Notes, Antibody reports), etc.