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FOR A RESPONSIBLE AND INNOVATIVE RESEARCH

REPLACE


REDUCE


REFINE

FC3R is the French reference center for all 3Rs-related matters. It aims to support responsible use of animals for scientific research and to promote alternative and innovative methods.

2025 3Rs prize for “Culture of care” and “Research”: call for applications!

The report on Replacement in France has just been published!

The results of the “Innovate, Replace, Share” call for projects are published.


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Next webinar September 18, 2025:
Tamoxifène : vers des administrations respectueuses du bien-être animal et reproductibilité scientifique

Opal Short Note Challenge!
The Opal will be awarded to the next 10 short notes that are accepted by the FC3R.

EVENTS

02.09.25 The TEATIME journey Shaping the future of lab animal monitoring Helsinki(Finlande) et en ligne

After four years of working closely together, our network on automated home-cage monitoring technologies is approaching the final stage of the Action, and we warmly invite you to join us for our conference.

03.09.25 Congress International Congress on Peer Review and Scientific Publication Chicago (USA)

The 10th International Congress on Peer Review and Scientific Publication, is held every 4 years.

04.09.25 webinar The Replacement Checklist for Grant Reviewers En ligne

This free 30-minute session is tailored for those who assess research proposals involving animal use. We’ll provide a practical checklist to help you ensure that all applications have robustly implemented Replacement in line with regulatory 3Rs requirements.

NEWS

Six reasons to replace Basement Membrane Extracts in research

04.07.25

BME, widely used in advanced cell culture and organoid research, are derived from mouse tumors and present significant ethical, scientific, and practical challenges.

SimLife, a new 3R approach to surgical training?

01.07.25

This innovation, based on cadaver perfusion, is rekindling reflection on the future of educational practices and helping to reduce the use of animals.

XeMo, the substitutive Xenopus Model

19.06.25

A consortium of aquatic model experts developed a Xenopus model substitute made from laboratory gloves.