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FOR A RESPONSIBLE AND INNOVATIVE RESEARCH

REPLACE


REDUCE


REFINE

FC3R is the French reference center for all 3Rs-related matters. It aims to support responsible use of animals for scientific research and to promote alternative and innovative methods.

Next webinar 10/16/2025:
Réduction : apport des banques de tissus et des bases de données

Opal Short Note Challenge!
The Opal will be awarded to the next 10 short notes that are accepted by the FC3R.

The call for projects "Refinement" is open !

Consult The report on Replacement in France

2025 3Rs prize for “Culture of care” and “Research”: call for applications!


The COST Action IMPROVE launches the survey NAM expert pool Database

EVENTS

08.10.25 training school Teaching the 3Rs: Train the trainers Porto (Portugal)

This is a Training School of Cost Action (CA21139) IMPROVE.

14.10.25 zebrafish webinar Colony Management Online

Speaker : TBC

14.10.25 Webinar Botulinum Neurotoxin Testing Online

Webinar on replacing animal use in botulinum neurotoxin (BoNT) testing

NEWS

Animal welfare at the heart of applied research

15.09.25

Solenn Percelay, Animal Welfare scientist, works to ensure that mouse welfare is integrated into everyday scientific and ethical considerations.

The Netherlands' transition to animal-free research

18.09.25

The launch of the Ombion center confirms the Netherlands' pioneering role in the transition to animal-free research.

Six reasons to replace Basement Membrane Extracts in research

04.07.25

BME, widely used in advanced cell culture and organoid research, are derived from mouse tumors and present significant ethical, scientific, and practical challenges.