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FC3R Reports and publications

The FC3R produces and contributes to scientific reports and publications that are submitted to peer review committees. These documents, developed by the FC3R or in collaboration with academic partners, contribute to the dissemination of knowledge and the promotion of the 3Rs principle (Replace, Reduce, Refine).

REPORTS

PEER-REVIEWED PUBLICATIONS

A call for preregistration of in vitro research : Pregistration as a tool to improve reproducibility and transparency.

Heinl C, Franco NH, Bert B, Siewert K, Movia D, Aruçi E, Ladeira C, Sanin AY, Neuhaus W, Kahlert UD, Ghosh M, Thomas A, Sotiropoulos A.
EMBO Rep 2026 April 17. DOI: 10.1038/s44319-026-00764-x

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Building bridges: Involvement of animal care staff and laboratory technicians in experimental planning and conduct of animal studies for better job satisfaction and science.

Gonzalez-Uarquin F, Jirkof P, Bert B, Hawkins P, Angelovski L, Baumgart J, Baumgart N, Cevik ÖS, Franco NH, Horata E, Kaura R, Neuhaus W, Riso B, Smith AJ, Sotiropoulos A, Vitale A, Schober S.
Lab Anim. 2026 Apr 14:236772251400976. DOI: 10.1177/00236772251400976

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Organoïdes, organes sur puce, complex in vitro model : définitions, applications, validation, éthique

Mottet G, Grassart A, Barthélemy P, Antignac C, Arrabal S, Bourdin A, Descroix S, De Vos J, Doutriaux A, Fabrega Q, Galaup A, Graff-Dubois S, Illiano S, Legallais C, Maisonneuve B, Piwnica D, Quéméneur E, Salentey V, Rozenberg J, Sotiropoulos A, Tomasi R, Vergnolle N, Devillier P.
Therapie. 2025 Jan-Feb;80(1):1-16. doi: 10.1016/j.therap.2024.12.003

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Organoids, organs-on-chips, complex in vitro model: Definitions, applications, validation, ethics

Mottet G, Grassart A, Barthélemy P, Antignac C, Arrabal S, Bourdin A, Descroix S, De Vos J, Doutriaux A, Fabrega Q, Galaup A, Graff-Dubois S, Illiano S, Legallais C, Maisonneuve B, Piwnica D, Quéméneur E, Salentey V, Rozenberg J, Sotiropoulos A, Tomasi R, Vergnolle N, Devillier P.
Therapie. 2025 Jan-Feb;80(1):17-31. 10.1016/j.therap.2024.12.002

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Toward a common interpretation of the 3Rs principles in animal research

Lauwereyns J, Bajramovic J, Bert B, Camenzind S, De Kock J, Elezović A, Erden S, Gonzalez-Uarquin F, Ulman YI, Hoffmann OI, Kitsara M, Kostomitsopoulos N, Neuhaus W, Petit-Demouliere B, Pollo S, Riso B, Schober S, Sotiropoulos A, Thomas A, Vitale A, Wilflingseder D, Ahluwalia A.
Lab Anim (NY). 2024 Dec;53(12):347-350. doi: 10.1038/s41684-024-01476-2

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